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Image Search Results
Journal: PLoS ONE
Article Title: Novel Antibody against a Glutamic Acid-Rich Human Fibrinogen-Like Protein 2-Derived Peptide near Ser91 Inhibits hfgl2 Prothrombinase Activity
doi: 10.1371/journal.pone.0094551
Figure Lengend Snippet: (A-D) The fibrin clot generation was evaluated through a one-stage clotting assay in FX, FVII, FII-deficient and normal plasma. The means of PCA units calculated for hfgl2 prothrombinase obtained from the c groups (EC+TNF) were assigned a 100%. The values in the histograms are the means of PCA units obtained from group n/group c ± S.E.M. In figure A and B, group d vs. group c, *** P <0.001 (n = 6). In figure D, group d vs. group c, * P <0.05 (n = 9). (E) The thrombin generation was evaluated using a Thermo Electron Fluoroskan Ascent fluorometer in FX-deficient plasma. The means of fluorescent units obtained from the c groups (TC+TNF) were assigned a 100%. The values in the histograms are the means of fluorescent units obtained from group n/group c ± S.E.M (n = 3). Group d vs. group c, *** P <0.001. EC: HUVECs, TNF: TNF-α, anti-NPG-12: anti-NPG-12 antibodies.
Article Snippet: Briefly, 100 μl of the HUVECs samples were mixed with 100 μl of FX,
Techniques: Coagulation, Clinical Proteomics